Application of platelet function testing to the bedside

Journal:Thrombosis and Haemostasis
ISSN:0340-6245
DOI:http://dx.doi.org/10.1160/TH09-06-0375
Issue:2010: 103/1 (Jan) pp. 1–249
Pages:29-33

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Article

Application of platelet function testing to the bedside

C. D. Williams (1), G. Cherala (1), V. L. Serebruany (2)

(1) Department of Pharmacy Practice, Oregon State University and Oregon Health and Science University College of Pharmacy, Portland, Oregon, USA; (2) HeartDrug Research, Johns Hopkins University, Towson, Maryland, USA

Summary

The ability to test platelet reactivity in clinical practice could help in making informed decisions on both initiation and titration of anti-platelet drug therapies. However, many barriers still remain to the effective implementation of such techniques. Many tests used in the research literature are not yet available for practical, clinical use. Platelet aggregometry, while informative and currently available for bedside use, needs additional research before routine clinical use can be recommended. This review will highlight and update contemporary issues of bedside platelet testing for the clinician and comment on future areas of clinical research.

Keywords

clopidogrel, Aspirin, platelet aggregation, platelet function tests, antiplatelet tests

DOI

http://dx.doi.org/10.1160/TH09-06-0375
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