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Treatment with rhBMP-2 of extreme radial bone atrophy secondary to fracture management in an Italian Greyhound

Journal:Veterinary and Comparative Orthopaedics and Traumatology (VCOT)
ISSN:0932-0814
DOI:http://dx.doi.org/10.3415/VCOT-07-04-0040
Issue:2008: Issue 1 2008
Pages:64-68

Treatment with rhBMP-2 of extreme radial bone atrophy secondary to fracture management in an Italian Greyhound

F. Bernard1, R. Furneaux1, C. Adrega Da Silva2, J.-F. Bardet2
1Surgery Unit, University College Dublin, Belfield, Dublin, Republic of Ireland 2Clinique Veterinain, Neuilly-sur-Seine, France

Summary

rhBMP-2 solution on a collagen sponge was placed along the diaphysis of an atrophicradius, which had a history of recurring fractures. Two months after rhBMP-2 treatment, new mineralized bone was present, which significantly increased the diameter of the radius and allowed the removal of the external skeletal fixator (ESF). Due to carpo-metacarpal joint compromise, a pancarpal arthrodesis was performed seven months later. At follow-up evaluation two years later the dog was only very mildly lame.

Keywords

Osteoporosis, dog, bone, atrophy, rhBMP

DOI

http://dx.doi.org/10.3415/VCOT-07-04-0040

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