Categorisation of bone marrow syndromes

Journal: Osteologie
ISSN: 1019-1291


Issue: Issues of 2017 (Vol. 26): Issue 2 2017 (59-130)
Pages: 62-66

Categorisation of bone marrow syndromes

U. Maus (1), J. Beckmann (2)

(1) Klinik für Orthopädie und spezielle Orthopädie, Universitätsklinik für Orthopädie und Unfallchirurgie, Pius Hospital, Carl-von-Ossietzky Universität Oldenburg, Oldenburg; (2) Sportklinik Stuttgart, Stuttgart


osteonecrosis, bone marrow edema, Bone marrow edema syndrome, transitoric osteoporosis


Bone marrow edema syndrome is a self-limiting disease, with a spontaneous resolution in up to 24 months. The bone marrow syndrome mostly affects middle-aged men with an age between 30 and 50 years, or women in the third trimester of pregnancy. The painful disease is often localised hip, knee or ankle joint. Magnetic resonance imaging (MRI) shows large homogenous bone marrow edema involving the femoral head and sometimes the femoral neck. A possible evolution in toward an osteonecrosis is still debated, the differentiation is sometimes challenging. Bone marrow edema is also described with other clinical entities, which are all characterized by the same findings in MRI. But the differentiation in different etiologies is clinical relevant for the decision about the therapy. The classification by different localizations is not useful for the clinical situation and therapy decision. Most authors prefer a diversification in mechanical, ischaemic and reactive or posttraumatic causes. The current article shows different kinds of bone marrow edema and bone marrow edema syndrome and explains the relevant criteria for differentiation.

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