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Therapeutic use of low molecular weight heparin for capillaritis alba

Journal:Phlebologie
ISSN:0939-978X
Issue:2008 (Vol. 37): Issue 5 2008 (227-282)
Pages:259-265

Therapeutic use of low molecular weight heparin for capillaritis alba

G. Hesse1; H. Kutzner2
1Hautarztpraxis München; 2Hautarztpraxis Friedrichshafen, Germany

Summary

The reason of the so called ulcerated capillaritis alba or idiopathic atrophie blanche is vasculopathy caused by severe venous hypertension. Thrombosed and rarificated vessels worsen the oxygenation, increase permanent inflammation and impede the necessary compression therapy. The anti-inflammatory effects of heparin alleviate pain and being independent from the antithrombotic ones it needs much lower doses for treatment. This anti-inflammatory effect is now becoming more important in clinical phlebology. Case studies of more than 50 patients and one prospective randomized study of 87 patients clearly demonstrate the ameliorated healing of ulcerated atrophie blanche. In our office we could document this positive effect with 22 patients. We present the pathophysiology of low molecular heparins for ulcerated capillaritis alba and our own experiences with it.

Keywords

low molecular weight heparin, Ulcerated capillaritis alba, vasculopathy, protective effects of heparin

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