(1) Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada; (2) Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada

(1) University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, UK

(1) Institute for Molecular Cardiovascular Research (IMCAR), RWTH Aachen University, Aachen, Germany

(1) HeartDrug(TM) Research Laboratories

(1) Institute for Pharmacology and Toxicology, Philipps-University Marburg, Germany; (2) Walther-Straub-Institute for Pharmacology and Toxicology, Ludwig-Maximilians UniversityMunich, Germany

(1) Department of Clinical Medicine, University of Insubria, Varese, Italy

(1) Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, Missouri, USA

(1) J. Recanati Autonomic Dysfunction CTR and the Thrombosis and Hemostasis Unit, Medicine, Rambam Health Care Campus, and Bruce Rappaport Faculty of Medicine, Technion-IIT, Haifa, Israel

(1) Department of Medical Biochemistry, Semmelweis University, Budapest, Hungary

(1) Klinik für Augenheilkunde, Klinikum der Johann-Wolfgang-Goethe-Universität Frankfurt am Main, Germany; (2) Medizinische Klinik I, Klinikum der Johann-Wolfgang-Goethe-Universität Frankfurt am Main, Germany; (3) III. Medizinische Klinik, Johannes-Gutenberg-Universität, Mainz, Germany; (4) Augenklinik des Klinikums Ludwigshafen, Ludwigshafen, Germany

(1) Department of Internal Medicine, Hospital Universitario Reina Sofía, Córdoba, Spain; (2) Department of Thrombosis, Istituto Cliinico Humanitas IRCCS, Rozzano, Milan, Italy; (3) Department of Internal Medicine, Ospedale Buonconsiglio Fatebenefratelli, Naples, Italy; (4) Department of Haematology, Rambam Medical Center, Haifa, Israel; (5) Departmentof Internal Medicine, Hospital Universitario Santa María de Rosell, Cartagena, Murcia, Spain; (6) Department of Internal Medicine, Hospital Universitario Joan XXIII de Tarragona,Tarragona, Spain; (7) Department of Internal Medicine, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain

(1) Department of Pharmacy, Brigham and Women’s Hospital, Harvard Medical School Boston, Massachusetts, USA; (2) Cardiovascular Division, Brigham and Women’s Hospital,Harvard Medical School Boston, Massachusetts, USA; (3) Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School Boston, Massachusetts, USA; (4) Information Systems, Brigham and Women’s Hospital, Harvard Medical School Boston, Massachusetts, USA; (5) Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

(1) Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands; (2) Department of Anesthesiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands; (3) Department of Laboratory of Clinical Immunology, Maastricht University Medical Centre, Maastricht, The Netherlands; (4) Department of Internal Medicine, Cardiovascular ResearchInstitute Maastricht (CARIM), Maastricht, The Netherlands

(1) Center for Health Quality, Outcomes and Economic Research, Bedford VA Medical Center, Bedford, Massachusetts, USA; (2) Department of Medicine, Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA; (3) Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA

(1) Consultant, Department of Haematology, Heart of England NHS Foundation Trust, Birmingham, UK; (2) Director, MMRx Consulting, Cheam, Surrey, UK; (3) Consultant, Departmentof Haematology, King's College Hospital, London, UK; (4) Consultant, Medical Assessment Unit, The Calderdale Royal Hospital, Halifax, UK; (5) Clinical Scientist, Departmentof Haematology, Barts and The London School of Medicine and Dentistry, London, UK; (6) Consultant, Department of Haematology, Derriford Hospital, Plymouth, UK; (7) Thrombosis Nurse Specialist, Scarborough Hospital, Scarborough, UK; (8) Thrombosis Nurse Specialist, Northampton General Hospital NHS Trust, Northampton, UK; (9) Statistical Consultant,London, UK; (10) Harry Smith, Medical Advisor, Sanofi Aventis UK*; (11) Special Advisor, Blood Policy Unit, Department of Health, London, UK; (12) Consultant, Departmentof Haematology, Warwick Hospital, Warwick, UK

(1) Thrombosis Unit, National Hemophilia Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Israel; (2) Neonatolgy, National Hemophilia Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Israel; (3) Pediatric Hematoloy, Safra Medical Center for Children, National Hemophilia Center, Tel Hashomer, Sackler School of Medicine, Tel Aviv University, Israel

(1) National Hemophilia Center, Sheba Medical Center, Tel-Hashomer, Israel; (2) Medical and Science Management, Novo Nordisk A/S, Bagsværd, Denmark; (3) Biostatistics, Novo Nordisk A/S, Bagsværd, Denmark*; (4) Deutsche Klinik für Diagnostik, Fachbereich Angiologie und Hämostaseologie, Wiesbaden, Germany†; (5) Laboratoire d’Hématologie, HôpitalCardiologique, Lille, France; (6) Zentrum für Innere Medizin, Klinikum der J.W. Goethe Universität, Frankfurt, Germany‡; (7) Abteilung für Hämostaseologie, Klinikum Innenstadt,der LMU München, München, Germany

(1) RTI Health Solutions, Manchester, UK; (2) Boehringer Ingelheim GmbH, Ingelheim am Rhein, Germany; (3) Boehringer Ingelheim Ltd, Bracknell, UK; (4) Department of Haematology, Queen's Medical Centre, University Hospital, Nottingham, UK; (5) Department of Orthopaedic Surgery, Fife Acute Hospitals NHS Trust, Queen Margaret Hospital, Dunfermline, UK

(1) Centre for Reproductive Biology, University of Edinburgh, UK; (2) Centre for Cardiovascular Sciences, University of Edinburgh, UK; (3) The Department of Respiratory and AllergyMedicine, University Hospital Umea, Sweden

(1) Department of Cardiology, St. Antonius Hospital Nieuwegein, the Netherlands; (2) Department of Hematology, Erasmus University Medical Center Rotterdam, the Netherlands; (3) Department of Clinical Chemistry, St. Antonius Hospital Nieuwegein, the Netherlands