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Articles prepublished January 27, 2012

A review of the treatment methods for cartilage defects

Journal:Veterinary and Comparative Orthopaedics and Traumatology (VCOT)
ISSN:0932-0814
DOI:http://dx.doi.org/10.3415/VCOT-11-05-0070
Pages:-

A review of the treatment methods for cartilage defects

R. M. Thiede (1), Y. Lu (1), M. D. Markel (1)

(1) Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin, USA

Summary

The purpose of this article is to provide a broad review of the literature related to the treatment of cartilage defects and degenerated cartilage in animals with some inferences to the treatment in humans. Methods range from the insertion of osteochondral tissue or cells to the application of radiofrequency or insertion of scaffolds and growth factors alone or in combination. Debridement, microfracture, radio frequency, and chondrocyte implantation are all methods normally utilized when treating smaller articular cartilage defects. Scaffolds and mosaicplasty are examples of methods to treat larger defects. This review will cover all major treatment methods currently used to treat articular cartilage defects.

Keywords

cartilage repair, Animal models, Cartilage defects, Treatment methods

DOI

http://dx.doi.org/10.3415/VCOT-11-05-0070

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